The advantage of having the CO2 cylinder outside is that the high pressure gauge will read around 850 lbs. This will stay there until all of the liquid CO2 in the cylinder has depleted. Then the pointer will begin to drop and when it reads in the red area, there is not much gas left.
With the cylinder in the kegerator, the pointer is always in the red and it is difficult to determine when the cylinder will be empty. Keg yield does not vary much.
Why do you want to switch to a beer gas mix? Are you now dispensing a nitrogenated product?
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